Our Technology
At Smart Tissues, we develop advanced regenerative therapies
Our technology intersects biofabrication, natural biomaterials and cell-free innovation
Our proprietary wound healing membrane is built using bioinks enriched with a chitosan derivative, a natural polymer known for its regenerative and antibacterial properties
What makes our technology unique is its ability to provide the optimal balance between promoting tissue regeneration and protecting against infection - a critical factor in treating chronic, non-healing wounds like diabetic foot ulcers (DFUs)
We apply multiple biofabrication methods, including 3D bioprinting, to tailor our products for specific clinical needs. Unlike traditional approaches, our solution is cell-free, scalable, and designed for real-world usability—making it easier for physicians to apply and more accessible for patients.
Our work is supported by cutting-edge research in collaboration with leading academic institutions, and is guided by a strong scientific, clinical, and engineering team committed to transforming the future of wound care and beyond.
Why Chitosan?
A Solution brought by Nature
Chitosan is a polysaccharide derived from chitin, the second most abundant polysaccharide in the world. Chitosan possesses inherent antimicrobial properties, and therefore is ideal to be used in biomedical applications such as wound healing biomaterials.
Chitosan has been shown promising antiviral properties, including its ability to induce resistance to viral infections in plants, animal cells, and in infected microbial cultures.
Presence of positively charged amine groups has been linked to antibacterial and bioactive properties of chitosan. Properties of chitosan, such as the mean polymerization degree, the degree of deacetylation, the positive charge, and the nature of chemical modifications of its molecule, strongly influence its biological activity.
We have identified the optimal processing and chemical modifications needed to preserve chitosan beneficial properties and exploit its full potential as bioink.
